Fluro-Octyl

Fluro-Octyl HPLC columns pair a fluorinated octyl chain with silica, giving reversed-phase retention with the altered selectivity that fluorine brings. Analysts use fluoro-octyl columns for fluorinated or halogenated analytes and other compounds where a hydrocarbon C8 column gives poor resolution.

Within the HPLC Columns catalogue this section carries 108 Vintage Chrom FSep Octyl and FSep Octyl HS listings. They are offered as 125 × 4 mm columns with 3 µm or 5 µm particles, on 60 Å silica for the HS variant and 100 Å for the standard phase.

Fluoro-octyl and fluoro-phenyl phases are often screened together, since the alkyl and aromatic ligands give different selectivities. Choose 3 µm when resolution is tight and 5 µm for everyday robustness. We can quote any FSep Octyl configuration on request.