C1

C1 HPLC columns carry the shortest alkyl chain in the reversed-phase family, a trimethylsilyl (TMS) bonding that gives low hydrophobic retention. Chemists use C1 HPLC columns for strongly hydrophobic analytes, large molecules and fast screening where C18 retains too much.

The 68 listings are Vintage Chrom Bond TMS columns in 125 × 4 mm format. Particle sizes run from 5 µm to 10 µm, with 60 Å and 100 Å pore options for each.

When a method on C8 or C4 still elutes late, moving down to a C1 column shortens retention without changing the mobile phase family. The 10 µm packings suit semi-preparative or robust routine work; 5 µm gives sharper peaks for analytical quantification. Ask for a quotation if your required dimension is not listed.